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Create your own personalized vacation with Thomas Cook flight and hotel deals.

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Group Travel Deals

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Go on holiday with a group of friends, co-workers or your club. Thomas Cook can get you there.

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Have a dream wedding in a romantic destination. Thomas Cook can help you find the right resort.

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Last Minute Vacation Deals

Last Minute Vacation Deals

Hurry book today don't miss out on these great deals and have a tan for the fall.

Summer Vacation Deals

Summer Vacation Deals

TOP 10 Destinations to go this summer

Resort Short Stay & City Getaway Deals

Vegas Short Stays

Can't take a full week off? We have the greatest prices on 3 - 5 day getaways..

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South America Cruise Vacations

South America Cruises
South America Cruises

Unusual ports and luxury cruise ships - an adventurous vacation

Choose South America.

South American cruises are adventures to unique and unusual destinations. The most popular itineraries feature the ports of Argentina and Chile as part of a trip around Cape Horn. Amazon River cruises feature jungle exploring and Brazilian beaches while Antarctic trips are full of once-in-a-lifetime experiences. Most Cape Horn cruises travel from Buenos Aires to Valparaiso but can be done in the other direction too. Manaus is the starting point for Amazon cruises while Antarctic cruises typically leave from Ushuaia.

Cruise to Buenos Aires or Rio de Janeiro.

Cruise through the majestic fjords and past massive glaciers along Chile's Pacific coast. Get up close to penguins in Puerto Madryn or climb volcanic hills on Antarctica. Explore wild, wind-swept Patagonia in Ushuaia or relax on the beautiful beaches of Rio de Janeiro.



South America Cruise Deals

Results 11-20 of 91
SOUTH AMERICA Azamara Quest 9 nights
$2598.00 + $319.00 (tax)Call to Book
SOUTH AMERICA Celebrity Xpedition 7 nights
$3549.00 + $113.00 (tax)Call to Book
SOUTH AMERICA Celebrity Xpedition 7 nights
$3549.00 + $113.00 (tax)Call to Book

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