Most Eastern Mediterranean itineraries either emphasize cruising around the sun-drenched islands of Greece or visiting the cultural gems that ring this end of Mediterranean. Regardless which of the two you choose, many cruises start and end in different cities so that as many ports as possible can be squeezed in to the itinerary. Venice and Rome are the most popular departure ports, but cruises also depart from Barcelona, Athens and Istanbul.
Soak up the sun on one the Greek islands like Mykonos, Santorini, Rhodes or Corfu. Get a taste of the Middle East in Alexandria, Egypt or Haifa, Israel. See where East meets West in bustling Istanbul. Walk the cobblestone streets of Dubrovnik or take a gondola along the canals of Venice.